ES2046196T3 - Derivados de azacicloalcanos, promotores de absorcion que contienen los derivados como ingrediente eficaz y preparaciones externas que contienen los promotores de absorcion. - Google Patents
Derivados de azacicloalcanos, promotores de absorcion que contienen los derivados como ingrediente eficaz y preparaciones externas que contienen los promotores de absorcion.Info
- Publication number
- ES2046196T3 ES2046196T3 ES198787200183T ES87200183T ES2046196T3 ES 2046196 T3 ES2046196 T3 ES 2046196T3 ES 198787200183 T ES198787200183 T ES 198787200183T ES 87200183 T ES87200183 T ES 87200183T ES 2046196 T3 ES2046196 T3 ES 2046196T3
- Authority
- ES
- Spain
- Prior art keywords
- derivatives
- absorption promoters
- absorption
- effective ingredient
- azacicloalcanos
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000004615 ingredient Substances 0.000 title abstract 2
- 229940124532 absorption promoter Drugs 0.000 title 2
- 238000002360 preparation method Methods 0.000 title 1
- 238000010521 absorption reaction Methods 0.000 abstract 4
- -1 AMINO GROUP Chemical group 0.000 abstract 1
- YZCKVEUIGOORGS-UHFFFAOYSA-N Hydrogen atom Chemical compound [H] YZCKVEUIGOORGS-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 229910052760 oxygen Chemical group 0.000 abstract 1
- 239000001301 oxygen Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/267—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/08—Oxygen atoms
- C07D223/10—Oxygen atoms attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/12—1,4-Thiazines; Hydrogenated 1,4-thiazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/06—Seven-membered rings having the hetero atoms in positions 1 and 4 not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP61079174A JPH0643390B2 (ja) | 1986-04-08 | 1986-04-08 | アザシクロアルカン誘導体 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2046196T3 true ES2046196T3 (es) | 1994-02-01 |
Family
ID=13682615
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES198787200183T Expired - Lifetime ES2046196T3 (es) | 1986-04-08 | 1987-02-07 | Derivados de azacicloalcanos, promotores de absorcion que contienen los derivados como ingrediente eficaz y preparaciones externas que contienen los promotores de absorcion. |
Country Status (14)
Country | Link |
---|---|
US (1) | US4882359A (en]) |
EP (1) | EP0241050B1 (en]) |
JP (1) | JPH0643390B2 (en]) |
KR (1) | KR910000164B1 (en]) |
CN (2) | CN1020605C (en]) |
AR (1) | AR245107A1 (en]) |
AT (1) | ATE81505T1 (en]) |
AU (1) | AU601402B2 (en]) |
CA (1) | CA1336597C (en]) |
DE (1) | DE3782182T2 (en]) |
ES (1) | ES2046196T3 (en]) |
GR (1) | GR3006768T3 (en]) |
SU (3) | SU1748644A3 (en]) |
WO (1) | WO1987006226A2 (en]) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3779833T2 (de) * | 1986-01-31 | 1993-02-04 | Whitby Research Inc | Zusammensetzungen enthaltend 1-substituierte azacycloalkane und deren verwendung. |
US5472946A (en) * | 1988-04-08 | 1995-12-05 | Peck; James V. | Transdermal penetration enhancers |
CA1334646C (en) * | 1988-04-08 | 1995-03-07 | James Vanolden Peck | Transdermal penetration enhancers |
US5234959A (en) * | 1988-04-08 | 1993-08-10 | Whitby Research, Inc. | Penetration enhancers for transdermal delivery of systemic agents |
US5041435A (en) * | 1988-08-13 | 1991-08-20 | Santen Pharmaceutical Co., Ltd. | Cyclic sulfur-containing compounds |
ES2063369T3 (es) * | 1989-08-03 | 1995-01-01 | Hisamitsu Pharmaceutical Co | Crema para la piel, para uso externo. |
IL91928A (en) * | 1989-10-08 | 1994-07-31 | Amrad Res & Dev | Pharmaceutical compositions containing prolactin |
US5070084A (en) * | 1990-02-26 | 1991-12-03 | Campbell James N | Treatment of sympathetically maintained pain |
US6559186B1 (en) | 1990-02-26 | 2003-05-06 | Arc 1, Inc. | Compositions and methods of treatment of sympathetically maintained pain |
FR2663932B1 (fr) * | 1990-06-29 | 1994-04-29 | Cird Galderma | N-alkyl oxo-1 et dioxo-1,1 thiamorpholinones-3 et leurs utilisations comme agents de penetration de composes actifs dans des compositions therapeutiques et cosmetiques. |
JPH078806B2 (ja) * | 1990-08-16 | 1995-02-01 | 旭化成工業株式会社 | カルシトニン類含有経鼻投与用乳剤 |
FR2666962B1 (fr) * | 1990-09-26 | 1996-06-14 | Oreal | Composition antifongique sous forme de spray sec. |
US5158763A (en) * | 1990-10-09 | 1992-10-27 | Colgate-Palmolive Company | Non-staining anti-bacterial oral composition |
JPH07595B2 (ja) * | 1990-10-31 | 1995-01-11 | 久光製薬株式会社 | アザシクロアルカン誘導体の製造方法 |
US5206386A (en) * | 1991-03-20 | 1993-04-27 | Isp Investments Inc. | Controlled release N-substituted pyrrolidone esters and process for the use thereof |
JP3090353B2 (ja) * | 1991-09-17 | 2000-09-18 | 旭化成工業株式会社 | パラチロイドホルモン類含有経鼻投与用乳剤 |
EP0608433B1 (en) * | 1992-07-13 | 2004-05-19 | Shiseido Company, Ltd. | Composition for dermatologic preparation |
WO1995011042A1 (fr) * | 1993-10-21 | 1995-04-27 | Hisamitsu Pharmaceutical Co., Inc. | Composition administree par voie nasale et preparation contenant celle-ci |
DE4337945A1 (de) * | 1993-11-06 | 1995-05-11 | Labtec Gmbh | Pflaster zur Behandlung von Nagelmykosen |
GB9325854D0 (en) * | 1993-12-17 | 1994-02-23 | Smithkline Beecham Corp | Porcess |
US6262117B1 (en) | 1999-02-18 | 2001-07-17 | Allergan Sales, Inc. | Method and composition for treating acne |
JP2000247911A (ja) | 1999-02-26 | 2000-09-12 | Hisamitsu Pharmaceut Co Inc | 大腸用吸収促進剤 |
JP4653282B2 (ja) * | 2000-05-23 | 2011-03-16 | 昭和薬品化工株式会社 | ミノサイクリン含有組成物 |
RU2311409C2 (ru) * | 2003-01-10 | 2007-11-27 | Ф.Хоффманн-Ля Рош Аг | Производные 2-пиперидона в качестве агонистов простагландина |
JP4504210B2 (ja) * | 2005-01-25 | 2010-07-14 | 花王株式会社 | 染毛剤組成物 |
US8026266B2 (en) | 2005-11-08 | 2011-09-27 | Arcion Therapeutics, Inc. | Treatment of length dependent neuropathy |
CN118141709B (zh) * | 2024-02-22 | 2025-04-22 | 北京逆之龄生物科技有限公司 | 一种抗衰老化妆品及其制备方法和应用 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE871154C (de) * | 1942-08-26 | 1953-03-19 | Basf Ag | Verfahren zur Herstellung oberflaechenwirksamer Verbindungen |
GB947910A (en) * | 1960-11-04 | 1964-01-29 | Gen Aniline & Film Corp | Surface active ethers of n-(hydroxymethyl)-lactams |
US3188317A (en) * | 1961-12-22 | 1965-06-08 | Dow Chemical Co | Oxazolidinone derivatives |
US3228955A (en) * | 1962-01-18 | 1966-01-11 | Dow Chemical Co | Certain substituted oxazolidinones and pyrrolidinones |
DE1177641B (de) * | 1962-06-12 | 1964-09-10 | Kalk Chemische Fabrik Gmbh | Verfahren zur Herstellung von N-(ª‰-Hydroxy-alkyl)-oxazolidonen-(4) bzw. deren Polyaether |
DE1241830B (de) * | 1962-11-02 | 1967-06-08 | Kalk Chemische Fabrik Gmbh | Verfahren zur Herstellung von AEthern des N-Methylol-2, 2, 5, 5-tetramethyloxazolidons-(4) |
US3232952A (en) * | 1963-09-20 | 1966-02-01 | Kalk Chemische Fabrik Gmbh | Di-(oxazolidinone-(4)-n-alkyl)-ethers |
DE1695846A1 (de) * | 1967-05-05 | 1971-05-13 | Schwarzkopf Gmbh Hans | Verfahren zur Darstellung von Thioaethern mit reduktiven Eigenschaften |
DE2114295A1 (de) * | 1970-03-27 | 1971-10-14 | Gaf Corp | Substituierte AEtherderivate des N-Hydroxymethyl-2-pyrrolidinon und Verfahren zu deren Herstellung |
DE2114251A1 (de) * | 1970-03-30 | 1971-10-14 | Gaf Corp | Tertiaere Aminomethylderivate des N-Hydroxymethyl-2-pyrrolidinon und Verfahren zu deren Herstellung |
US3956313A (en) * | 1970-04-13 | 1976-05-11 | Gaf Corporation | N-(substituted-thiomethyl)-2-pyrrolidinones |
US3991203A (en) * | 1975-06-19 | 1976-11-09 | Nelson Research & Development Company | Vehicle composition containing 1-substituted azacyclopentan-2-ones |
US4415563A (en) * | 1980-04-04 | 1983-11-15 | Nelson Research & Development Company | Vehicle composition containing 1-substituted azacyclononan-2-ones |
US4424210A (en) * | 1980-04-04 | 1984-01-03 | Nelson Research & Development Company | Vehicle composition containing 1-substituted azacycloalkan-2-ones |
US4444762A (en) * | 1980-04-04 | 1984-04-24 | Nelson Research & Development Company | Vehicle composition containing 1-substituted azacyclopentan-2-ones |
US4423040A (en) * | 1980-04-04 | 1983-12-27 | Nelson Research & Development Company | Vehicle composition containing 1-substituted azacyclohexan-2-ones |
FR2525106B1 (fr) * | 1982-04-15 | 1985-06-07 | Oreal | Composition cosmetique contenant en tant qu'agent actif sur l'elasticite et la souplesse de la peau, de la thiamorpholinone ou l'un de ses derives |
FR2525220A1 (fr) * | 1982-04-15 | 1983-10-21 | Oreal | Nouveaux derives substitues de la thiamorpholinone et leurs procedes de preparation |
US4450102A (en) * | 1982-11-02 | 1984-05-22 | Phillips Petroleum Company | Sulfur based metal cleaners and corrosion inhibitors |
-
1986
- 1986-04-08 JP JP61079174A patent/JPH0643390B2/ja not_active Expired - Lifetime
-
1987
- 1987-02-07 EP EP87200183A patent/EP0241050B1/en not_active Expired - Lifetime
- 1987-02-07 ES ES198787200183T patent/ES2046196T3/es not_active Expired - Lifetime
- 1987-02-07 AT AT87200183T patent/ATE81505T1/de not_active IP Right Cessation
- 1987-02-07 DE DE8787200183T patent/DE3782182T2/de not_active Expired - Lifetime
- 1987-02-10 CA CA000529377A patent/CA1336597C/en not_active Expired - Fee Related
- 1987-02-10 WO PCT/JP1987/000086 patent/WO1987006226A2/en unknown
- 1987-02-10 AU AU70207/87A patent/AU601402B2/en not_active Ceased
- 1987-02-10 KR KR1019870701153A patent/KR910000164B1/ko not_active Expired
- 1987-02-11 AR AR87306713A patent/AR245107A1/es active
- 1987-02-12 CN CN91109720A patent/CN1020605C/zh not_active Expired - Lifetime
- 1987-02-12 CN CN87100666A patent/CN1018452B/zh not_active Expired
- 1987-11-18 US US07/131,193 patent/US4882359A/en not_active Expired - Lifetime
- 1987-12-07 SU SU874203780A patent/SU1748644A3/ru active
-
1989
- 1989-02-13 SU SU894613462A patent/SU1750422A3/ru active
- 1989-02-27 SU SU894613514A patent/SU1750423A3/ru active
-
1993
- 1993-01-13 GR GR930400029T patent/GR3006768T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0241050B1 (en) | 1992-10-14 |
JPS62238261A (ja) | 1987-10-19 |
AR245107A1 (es) | 1993-12-30 |
US4882359A (en) | 1989-11-21 |
CN1018452B (zh) | 1992-09-30 |
DE3782182D1 (de) | 1992-11-19 |
EP0241050A3 (en) | 1988-12-28 |
KR880701227A (ko) | 1988-07-26 |
SU1748644A3 (ru) | 1992-07-15 |
WO1987006226A3 (en) | 1988-04-07 |
AU601402B2 (en) | 1990-09-13 |
SU1750422A3 (ru) | 1992-07-23 |
AU7020787A (en) | 1987-11-09 |
GR3006768T3 (en]) | 1993-06-30 |
JPH0643390B2 (ja) | 1994-06-08 |
DE3782182T2 (de) | 1993-02-25 |
EP0241050A2 (en) | 1987-10-14 |
CN1060287A (zh) | 1992-04-15 |
CN1020605C (zh) | 1993-05-12 |
CA1336597C (en) | 1995-08-08 |
KR910000164B1 (ko) | 1991-01-21 |
ATE81505T1 (de) | 1992-10-15 |
CN87100666A (zh) | 1987-10-21 |
WO1987006226A2 (en) | 1987-10-22 |
SU1750423A3 (ru) | 1992-07-23 |
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